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Not merely quiescent: telomeres in quiescent HSCs.

aging

senescence

stem cell

Authors: Ayako A. Nakamura-Ishizu, Toshio T. Suda
Published: 11/21/2014, Blood

Abstract

In this issue of Blood, Wang et al elegantly show that telomere shortening results in DNA damage that induces apoptosis and senescence in quiescent hematopoietic stem cells (HSCs).

PubMed Full Text